Interaction of Transuranium Elements with Biologically Important Ligands: Structural and Spectroscopic Evidence for Nucleotide Coordination to Plutonium

The first complex of a transuranium element (tetravalent plutonium) with nucleotide (deoxycytidinemonophosphate, dCMP) was synthesized and structurally characterized. The crystal structure of [Pu4(NO3)8(HdCMP)4(H2O)8](NO3)4·2H2O consists of complex cations [Pu4(NO3)8(HdCMP)4(H2O)8]4+, NO3− anions, and water molecules. There are two crystallographically independent Pu atoms in the structure, both having similar surroundings. Each of the Pu atoms is coordinated by three O atoms of phosphate groups belonging to three different (HdCMP)− anions, two bidentate nitrate anions, and two water molecules. The crystal structure is confirmed by IR and UV/vis/near-IR spectroscopic data.