CPDB

The Carcinogenic Potency Database (CPDB) is a unique and widely used international resource of the results of 6540 chronic, long-term animal cancer tests on 1547 chemicals. The CPDB provides easy access to the bioassay literature, with qualitative and quantitative analyses of both positive and negative experiments that have been published over the past 50 years in the general literature through 2001 and by the National Cancer Institute/National Toxicology Program through 2004. The CPDB standardizes the diverse literature of cancer bioassays that vary widely in protocol, histopathological examination and nomenclature, and in the published author’s choices of what information to provide in their papers. Results are reported in the CPDB for tests in rats, mice, hamsters, dogs, and nonhuman primates.

致癌性潜力数据库（Carcinogenic Potency Database，CPDB）是一款独特且被广泛应用的国际性科研资源，收录了针对1547种化学物质开展的6540项慢性长期动物致癌试验的结果。该数据库可便捷获取致癌生物检测相关文献资料，涵盖了过去50年间、截至2001年的通用学术文献中发表的全部阳性与阴性试验的定性与定量分析结果，以及美国国家癌症研究所（National Cancer Institute）/国家毒理学计划（National Toxicology Program）截至2004年收录的同类试验数据。致癌性潜力数据库对异质性极强的癌症生物检测文献进行了标准化统一处理——这类文献在试验方案、组织病理学检查流程与命名规范，乃至论文作者自主选择的报告信息维度上均存在显著差异。数据库中收录了大鼠、小鼠、仓鼠、犬类以及非人灵长类动物的致癌试验结果。