Started in 2007, the Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-ethnicity (SAPPHIRE) is one of the largest asthma cohort studies in the United States. Its overarching goal is
Objective: Genetic background and environmental stimuli play an important role in asthma, which is an individual’s hyper-responsiveness to these stimuli leading to airway inflammation. Autophag
Background Regular use of inhaled corticosteroids (ICS) in patients with obstructive lung diseases has been associated with a higher risk of pneumonia, particularly in COPD. The risk of pneumonia has
Linear mixed models jointly modeling MCK and HDE. Linear mixed models with random intercepts for each individual model the association between the top fifteen RAO associated SNPs that were also eSNPs
We compared genomic DNA methylation patterns and gene expression in African American children with persistent atopic asthma versus healthy controls. We identified 119 differentially methylated regions
