A High-Performance Biodegradable Mg-Zn-Ca-Sn Alloy: Achieving Synergistic Improvement via Extrusion and Microstructural Design

This dataset contains the high-resolution original images for Figures 12, 13 and 14 of the article entitled “A High-Performance Biodegradable Mg-Zn-Ca-Sn Alloy: Achieving Synergistic Improvement via Extrusion and Microstructural Design” (Acta Biomaterialia).
Background and purpose:
This study reports a novel low‑alloyed Mg‑1.2Zn‑0.32Ca‑0.25Sn (ZXT100) alloy that achieves an excellent balance of high yield strength (~349 MPa) and low degradation rate (~0.209 mm/y) through extrusion temperature optimization. The alloy also exhibits favorable biocompatibility in vitro and in vivo, making it a promising candidate for load‑bearing biodegradable orthopedic implants.

Data description:
The dataset comprises the following original, unmodified image files:

Fig. 12 – Subcutaneous implantation results in rats (X‑ray images, gross pathology photographs, and H&E/Masson’s trichrome staining of skin and subcutaneous tissues).

Fig. 13 – In vivo osteogenic performance and bone integration of implanted screws in rabbit femoral condyles (X‑ray images, micro‑CT reconstructions, and quantitative bone‑related parameters).

Fig. 14 – Histological and immunohistochemical assessment of peri‑implant osseous tissue (H&E staining, Masson’s trichrome staining, and immunohistochemical staining for Col‑I and OCN).

These images are presented at the highest available resolution to allow readers to examine the fine histological details and micro‑CT reconstructions that support the paper‘s conclusions.