Data from: A missense mutation in SLC45A2 is associated with albinism in several small long haired dog breeds

SLC45A2 genotypes and phenotypes of albino and control drogsTwo missense mutations were observed in an albino dog: P250L in exon 3 and G493D in exon 7 of SLC45A2. The genotypes of all the tested albino and control dogs for these two mutations and their coat colours are included in the file.SLC45A2 SNP Summery JOH-2014-205.R1.xlsxSupplemental Table 1:Primers, annealing temperatures and the fragment of the SLC45A2 gene amplified. Supplemental Table 1-JOH-2014-205.R1.docxSupplemental Figure 1-A topology prediction comparison for SLC45A2A topology prediction comparison for SLC45A2 was carried out using TMHMM (v. 2.0; http://www.cbs.dtu.dk/services/ TMHMM-2.0/). a) The topology prediction for a cream Poodle. b) The topology prediction for an albino Lhasa Apso. The boxed regions indicate the eleventh transmembrane domain of SLC45A2 where the amino acid 493 is located. Comparison of the two panels clearly shows that the eleventh transmembrane domain of the albino Lhasa Apso has an altered structure.Supplemental Figure 1-JOH-2014-205.R1.jpg