Adult-onset autosomal dominant leukodystrophy (ADLD) is a slowly progressive neurological disorder characterized by autonomic dysfunction, followed by cerebellar and pyramidal features. ADLD is caused

NIAID Data Ecosystem60

Extrachromosomal circular SUZ12 amplicon dictates retinoblastoma progression through reprogramming H3K27 methylation [CUT&Tag]

视网膜母细胞瘤分子机制

表观遗传调控与肿瘤进展

Extrachromosomal circular DNA (eccDNA) is double-stranded circular DNA that is derived from but independent of chromosomal DNA. Owing to its nonchromosomal inheritance, eccDNA facilitates the amplific

NIAID Data Ecosystem40

Dissecting transcriptional and chromatin accessibility heterogeneity of proliferating cone precursors in human retinoblastoma tumours by single cell sequencing [scATAC-seq]

单细胞分析

视网膜母细胞瘤分子机制

Background: Retinoblastoma (Rb) is a malignant neoplasm arising during retinal development from mutations in the RB1 gene. Loss or inactivation of both copies of RB1 results in initiation of retinobla

NIAID Data Ecosystem60

MOESM4 of A genomic analysis and transcriptomic atlas of gene expression in Psoroptes ovis reveals feeding- and stage-specific patterns of allergen expression

寄生虫疾病与病理

基因组表达谱分析

Additional file 4. Gene IDs for all P. ovis genes attributed to each WHO/IUIS allergen groups.

NIAID Data Ecosystem40