LEAP ITN032AD: Induction of Tolerance through Early Introduction of Peanut in High-Risk Children, LEAP-On ITN049AD: The Persistence of Oral Tolerance Induction to Peanut and Its Immunological Basis

ITN032AD: This study will evaluate whether early exposure to peanuts promotes tolerance and provides protection from developing peanut allergy in children who are allergic to eggs or who have severe eczema. ITN049AD: This study will evaluate persistent tolerance to peanut by assessing the effect of 12 months of cessation of peanut consumption after 5 years of consumption versus continued avoidance of peanut.