Cellular and molecular mechanisms underlying granulosa cell tumor induced by constitutively activated TGFB signaling
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https://www.ncbi.nlm.nih.gov/sra/SRP344269
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资源简介:
Mice harboring constitutively activated TGFÃ signaling (TGFBR1-CA) develop ovarian GCTs that phenocopy the hormonal and several molecular characteristics of human GCTs. The goal of this study is to determine molecular alterations in the ovary upon TGFÃ signaling activation. We performed Next-generation sequencing (NGS) analysis of ovaries from TGFBR1-CA mice and age-matched controls during tumor formation Overall design: Ovarian mRNA profiles of 30-day old TGFBR1-CA mice and control mice
创建时间:
2022-05-21



