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Cryo-EM structure of eSaCas9_NNG-guide RNA-target DNA complex in an interrogation state

NIAID Data Ecosystem2026-05-10 收录

CRISPR-Cas结构生物学

冷冻电镜蛋白质复合体

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https://www.rcsb.org/structure/8ZCY 数据链接链接失效反馈

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Cryo-EM structure of eSaCas9_NNG-guide RNA-target DNA complex in an interrogation state

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创建时间：

2026-04-15

CRISPR-Cas结构生物学

基因编辑机制

Crystal structure of the Cas12i1-crRNA binary complex Descriptor: 12i1, CITRIC ACID, RNA (3-MER), ... Authors: Zhang, B, Luo, D.Y, Li, Y, OuYang, S.Y. Deposit date: 2020-10-07 Release date: 2021-05-19

Protein Data Bank Japan2024-10-23 更新110

SpCas9 with 17-bp R-loop containing 2 terminal mismatches (State I - pre-activation)

CRISPR-Cas结构生物学

基因编辑机制

SpCas9 with 17-bp R-loop containing 2 terminal mismatches (State I - pre-activation)

NIAID Data Ecosystem30

Crystal structure of E. coli Cascade bound to a PAM-containing dsDNA target at 2.45 angstrom resolution.

CRISPR-Cas结构生物学

PAM识别机制解析

Crystal structure of E. coli Cascade bound to a PAM-containing dsDNA target at 2.45 angstrom resolution. Descriptor: CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR syst

Protein Data Bank Japan2023-09-27 更新20

type I-C Cascade bound to ssDNA target

CRISPR-Cas结构生物学

R-loop形成机制

type I-C Cascade bound to ssDNA target Descriptor: CRISPR-associated protein, CT1133 family, TM1801 family, ... Authors: O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W.

Protein Data Bank Japan2025-05-28 更新30

Cryo-EM structure of Cas7-11-crRNA-Csx29 ternary complex

CRISPR-Cas结构生物学

冷冻电镜结构解析

Cryo-EM structure of Cas7-11-crRNA-Csx29 ternary complex Descriptor: CHAT domain-containing protein, CRISPR-associated RAMP family protein, crRNA (38-MER) Authors: Huo, Y, Dong, Q, Zhao, H, Jiang, T.

Protein Data Bank Japan2024-10-16 更新30

Cryo-EM structure of eSaCas9_NNG-guide RNA-target DNA complex in an interrogation state

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