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Species-specific processing of long noncoding RNAs contributes to non-conserved functions in human and mouse stem cells

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=410b19b82eb9bf4ea5b98281b696a14b
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资源简介:
Subcellular RNA-seq datasets are used for genome-wide RNA localization analysis. We find different subcellular localization of lncRNAs in human and mouse stem cells. FAST, one of conserved lncRNAs with different localizations, is validated to be important for stem cell pluripotency. Futher, splicing factor PPIE is revealed to regulate RNA processing and localization.
提供机构:
Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences
创建时间:
2022-02-20
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