Base-Level Resolution Run-On Sequencing in Osteoclast Precursor Cells. Base-Level Resolution Run-On Sequencing in Osteoclast Precursor Cells

To understand the pathogenic mechanisms of bone erosion in rheumatoid arthritis (RA), we investigated osteoclast-specific epigenetic programs, RANKL-responsive super-enhancers (SEs) and SE-associated enhancer RNAs (SE-eRNAs) in human osteoclasts. This dataset contains precision run-on sequencing (PRO-seq) data performed to detect SE-eRNA transcription activity. Overall design: PROseq, RANKL and Control