DNA replication occurs in a defined temporal order known as the replication-timing (RT) program. RT is regulated during development in discrete chromosomal units, coordinated with transcriptional acti
In this experiment, we sought to identify how topological organization changes at HoxA cluster in WT, MAZ HoxA(Δ5|6) and CTCF (Δ5|6:6|7) cells during differentiation of mouse embryonic stem cells (ESC
This supplemental file shows the genomic structure by MDS (v2, v3, v4), the selected DNA loops, and the list of genes contained therein. Also included are the consistency of selected DNA loops with Ch