Temporal analysis of Notch requirement for embryonic DA neuron specification in the VNC.

Tabular overview of analysis of DA neurons in the VNC after conditional removal of Notch at different phases of development. Presented are the percentages of affected neuromeres or hemineuromeres of H-cells, paramedial (PM) and dorsal lateral (DL) cells when Notch function is removed at St8, St9–10 and St10–11 of embryonic development. Notch removal during St10–11 of embryogenesis results in a shift towards higher percentage of H-cell duplication and lower percentage of segments containing more than 2 H-cells as compared to when Notch function is removed during St9–10 of embryogenesis, suggesting that sibling cell fate specification involving Notch occurs primarily at around St10–11 for the H-cells.