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Genome wide analysis of human iPS cell lines generated with non-integrative plasmids and knock-down of P53 gene

ChEBI2013-12-31 更新2026-07-21 收录

iPSC重编程

P53基因功能分析

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-48665 数据链接链接失效反馈

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资源简介：

Genome wide analysis of human iPS cell lines generated with non-integrative plasmids and knock-down of P53 gene

应用场景：

创建时间：

2013-12-31

干细胞多能性调控

iPSC重编程

Polycomb group (PcG) proteins comprise a large group of evolutionary conserved factors with essential roles for embryonic development and adult stem cell function. PcG proteins constitute two main mul

NIAID Data Ecosystem140

The Nucleolar Remodeling is Required for the of Mouse Fibroblasts Reprogramming to iPSC [ATAC-Seq]

iPSC重编程

核仁重塑

The nucleolus is a membraneless organelle responsible for ribosome biogenesis, perinuclear heterochromatin formation, and genome stability regulation. However, how cell fate decision occurs, including

NIAID Data Ecosystem50

Error-free and error-prone DNA repair gene expression through reprogramming and passage in human iPS cells. Error-free and error-prone DNA repair gene expression through reprogramming and passage in human iPS cells

iPSC重编程

病毒基因表达调控

Medical applications of human iPS cells(hiPSC) are evolving, but detailed elucidation of the mechanisms of reprogramming remains to be elucidated. Reprogramming is accompanied by an increase in the ex

NIAID Data Ecosystem40

Functionally distinct roles for TET-oxidized 5-methylcytosine bases in somatic reprogramming to pluripotency [RNA-Seq]

iPSC重编程

DNA去甲基化机制

Active DNA demethylation via Ten-eleven Translocation (TET) family enzymes is essential for epigenetic reprogramming in cell state transitions. TET enzymes catalyze up to three successive oxidations o

NIAID Data Ecosystem80

C/EBPα poises B cells for rapid reprogramming into iPS cells [RNA-Seq]

iPSC重编程

B细胞转化

C/EBPα induces transdifferentiation of B cells into macrophages at high efficiencies and enhances reprogramming into induced pluripotent stem cells (iPSCs) when co-expressed with Oct4, Sox2, Klf4 and

NIAID Data Ecosystem50

Genome wide analysis of human iPS cell lines generated with non-integrative plasmids and knock-down of P53 gene

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