TNF-a induced gene expression in epithelial cell lines
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE136439
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资源简介:
TNF-a is elevated in a variety of inflammatory disease involving epithelial tissues. To better understand the the impact of TNF-a on epithelial biology, 3 epithelial cell lines were cultured with and without TNFa and the transcriptomes compared using were profiled using Affymetrix GeneChip® HG-U133+2 array or HG-U133+PM arrays. Three epithelial cell lines (A549, HT-29, 293) and K562 (mylegenous leukemia) cell line were cultured in 6 replicates for 4 hrs with and without TNF-a and transcriptomes were assessed using Affymetrix GeneChip HT HG-U133+ PM 96 array plates. A list of genes from TNF-stimulated cultured primary human keratinocytes were also obtained for the experiment (original historical dataset not available). Data from K562 were not included in the summary gene set for TNF stimulation.
创建时间:
2019-12-16



