RNA sequencing of JCPyV infection in primary human astrocytes

Research in JCPyV infection of primary astrocytes is limited. However, viral infection in a transformed glial cell line (SVGAs), mostly composed of astrocytes, is well studied. RNA sequencing was performed at 24 hours post infection (hpi), 48 hpi, and 96 hpi. Timepoints established to be important in both cell types in the JCPyV infectious cycle. Comparitive analysis using RNA sequencing of JCPyV infection during varying timepoints of infection in primary astrocytes versus a transformed glial cell line, mostly composed of astrocytes