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Quantitative assessments of the anti-proliferative activity of (A) combinations of metal-chelating agents and (B) their iron (Fe) and copper (Cu) complexes that were formed at an metal binding equivalent of 1 in MCF-7 cells.

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Figshare2015-12-02 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_Quantitative_assessments_of_the_anti_proliferative_activity_of_A_combinations_of_metal_chelating_agents_and_B_their_iron_Fe_and_copper_Cu_complexes_that_were_formed_at_an_metal_binding_equivalent_of_1_in_MCF_7_cells_/940222
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All of the studied compounds and their combinations were incubated with MCF-7 cells for 72 h at 37°C at a concentration corresponding to their IC50 value. The combination index (CI) values were calculated using the Chou and Talalay method from n≥4 experiments using CalcuSyn 2.0 software; CI 1 indicate synergism, an additive effect, or antagonism, respectively. Statistical significance (ANOVA): *p0.05, **p0.01, ***p
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2015-12-02
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