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Crystal structure of human FXR in complex with (2S)-2-[2-(4-chlorophenyl)-1H-benzimidazol-1-yl]-N,2-dicyclohexylethanamide

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Protein Data Bank Japan2024-04-03 更新2026-03-21 收录
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Crystal structure of human FXR in complex with (2S)-2-[2-(4-chlorophenyl)-1H-benzimidazol-1-yl]-N,2-dicyclohexylethanamide Descriptor: (2S)-2-[2-(4-chlorophenyl)-1H-benzimidazol-1-yl]-N,2-dicyclohexylethanamide, Bile acid receptor, peptide of Nuclear receptor coactivator 1 Authors: Rudolph, M.G. Deposit date: 2010-08-25 Release date: 2010-12-29 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes Bioorg.Med.Chem.Lett., 21, 2010
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2010-08-25
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