Summary of MAb binding to DENV-1 DIII mutants expressed on the surface of yeast.

Values shown were achieved by dividing the total fluorescence product (percent positive population×mean linear fluorescence intensity) of a mutant for each individual antibody by the total fluorescence product of the wild type DIII×100. Values in bold indicate reductions in mAb binding of greater than or equal to 80% for a given mutation. Underlined values show a reduction between 50 and 79%. The results are the average of between three and five independent experiments for each mutant and each antibody.