T2* Measurements.

Shows a comparison of the absolute T2* values in the different mouse groups and the p-values comparing different groups using a two-tailed Students t-test. This data indicates that sufficient USPIO-PEG-Aβ1-42 is able to cross the BBB in vivo and result in T2* changes in USPIO-PEG-Aβ1-42 injected APP/PS1 mice, which can be attributed to specific binding to Aβ plaques, given the significantly lower T2* measurements in areas of the brain affected with Aβ deposition (cortex and hippocampus).