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Effect of the IRE1a-XBP1 pathway inhibition during T helper 2 differentiation

ChEBI2018-07-20 更新2026-07-12 收录

细胞分化机制

内质网应激

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-6894 数据链接链接失效反馈

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Effect of the IRE1a-XBP1 pathway inhibition during T helper 2 differentiation

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创建时间：

2018-07-20

毒理学

细胞分化机制

TCDD increased expression of numerous differentiation specific genes and decreased expression of numerous genes involved in mitochondrial health and redox homeostasis 8 total samples - 4 control (100%

NIAID Data Ecosystem70

XBP1 links ER stress to intestinal inflammation

肠道炎症基因表达调控

内质网应激

XBP1 is the transcriptino factor that is activated by the ER stress. XBP1 is known to induce the ER dexpansion and increase the expression of the ER chaperone genes to prtect the cell from the ER stre

NIAID Data Ecosystem50

Stromal-to-Epithelial Transition during Postpartum Endometrial Regeneration

子宫内膜再生

细胞分化机制

Endometrium is the inner lining of the uterus which is composed of epithelial and stromal tissue compartments enclosed by the two smooth muscle layers of the myometrium. In women, much of the endometr

Figshare2016-01-19 更新30

Lack of affinity signature for germinal center cells that have initiated plasma cell differentiation (Figure2)

细胞分化机制

抗体亲和力成熟

Long-lived plasma cells (PCs) secrete antibodies that can provide sustained immunity against infection. It has been proposed that high affinity cells are preferentially selected into this compartment,

NIAID Data Ecosystem50

input_fig1_C_D_S3A_GRP94_Hsp90_Hsp40

内质网应激

热休克蛋白功能

This dataset contains data used to generate panels 1C and 1D for GRP94, Hsp90 and Hsp40 in a preprint manuscript from the Misteli Lab at the National Cancer Institute/NIH. Title: Activation of endopla

Figshare2023-03-10 更新50

Effect of the IRE1a-XBP1 pathway inhibition during T helper 2 differentiation

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