Inducible degradation-coupled phosphoproteomics identifies PP2A-Rts1 as a novel eisosome regulator
收藏NIAID Data Ecosystem2026-05-01 收录
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资源简介：
We developed and validated a workflow in S. cerevisiae combining auxin-inducible protein degradation with LC-MS/MS phosphoproteomics and used it to identify candidate phosphatase substrates during mitosis, when kinase activity is high. Our results revealed that PP2A-Rts1 influences dephosphorylation of numerous proteins in mitosis, including multiple subunits of the plasma membrane-associated eisosome complex.
创建时间：
2023-10-24
