Defining Gene Signatures for Protective Immunity to Tuberculosis in the Rhesus Macaque Model

ChEBI2018-12-16 更新2026-07-12 收录

牛结核病与副结核病免疫机制

基因表达特征识别

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-7558 数据链接链接失效反馈

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Defining Gene Signatures for Protective Immunity to Tuberculosis in the Rhesus Macaque Model

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2018-12-16

An evolutionary recent IFN-IL-6-CEBP axis is linked to monocyte expansion and tuberculosis severity in humans.

牛结核病与副结核病免疫机制

谱系分化调控

Monocyte counts are increased during human tuberculosis (TB) but it has not been determined whether Mycobacterium tuberculosis (Mtb) directly regulates myeloid commitment. We demonstrated that exposur

NIAID Data Ecosystem120

The interaction of macrophages and CD8 T cells in bronchoalveolar lavage fluid is associated with latent tuberculosis infection

牛结核病与副结核病免疫机制

单细胞免疫组学

Mycobacterium tuberculosis (Mtb) infection, including active tuberculosis (TB) and latent Mtb infection (LTBI), leads to diverse outcomes owing to different host immune responses. However, the immune

Taylor & Francis Group2024-02-14 更新60

O-mannosylation of the Mycobacterium tuberculosis Adhesin Apa Is Crucial for T Cell Antigenicity during Infection but Is Expendable for Protection

牛结核病与副结核病免疫机制

糖基化疫苗设计

Glycosylation is the most abundant post-translational polypeptide chain modification in nature. Although carbohydrate modification of protein antigens from many microbial pathogens constitutes importa

Figshare2016-01-18 更新30

Novel Role for Macrophage Galactose-type Lectin-1 to Regulate Innate Immunity against Mycobacterium tuberculosis

牛结核病与副结核病免疫机制

先天免疫受体

Tuberculosis (TB) caused by infection with Mycobacterium tuberculosis (Mtb) is characterized by inflammatory pathology and poorly understood mechanisms of innate immunity. Pattern recognition receptor

NIAID Data Ecosystem70

Data_Sheet_1_Mycobacterium smegmatis Bacteria Expressing Mycobacterium tuberculosis-Specific Rv1954A Induce Macrophage Activation and Modulate the Immune Response.pdf

牛结核病与副结核病免疫机制

宿主-病原体相互作用

Mycobacterium tuberculosis (M. tb), the intracellular pathogen causing tuberculosis, has developed mechanisms that endow infectivity and allow it to modulate host immune response for its survival. Gen

NIAID Data Ecosystem60

Defining Gene Signatures for Protective Immunity to Tuberculosis in the Rhesus Macaque Model

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