BET bromodomain inhibitors synergize with ATR inhibitors to induce DNA damage, apoptosis, senescence-associated secretory pathway and ER stress in Myc- induced lymphoma cells. Mus musculus
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA301706
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资源简介:
The aim of the project was to determine the expression profiles of murine Myc-driven lymphpma cells (Lambda-820) treated with vehicle (DMSO, 1:1000), a BET inhibitor (RVX2135), an ATR inhibitor (VE-821) or a combination of RVX2135 and VE-821. All experimnets were performed in presence of 10uM Q-VD-OPH to block apoptosis. Cells were harvested 24 h after treatment start. Overall design: 4 samples (DMSO, RVX2135, VE-821 or RVX2135/VE-821) in duplicates
创建时间:
2015-11-10



