Displayed are means±SEM, Dunnett’s adjusted p-values of one respective CaV3.3 variant vs. WT, and the one-way ANOVA p-values of WT vs. the four CACNA1I variants. * p (S1_Table.XLSX)
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channel plays a critical role in regulating the resting membrane potential and integrating synaptic transmission. Variants of HCN1 have been r