11b-Hydroxysteroid Dehydrogenase Type I in complex with inhibitor
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https://pdbj.org/mine/summary/4c7j
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11b-Hydroxysteroid Dehydrogenase Type I in complex with inhibitor Descriptor: 4-cyclopropyl-2-(2-hydroxyethyloxy)-N-[(1S,3R)-5-oxidanyl-2-adamantyl]-1,3-thiazole-5-carboxamide, CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Goldberg, F.W, Dossetter, A.G, Scott, J.S, Robb, G.R, Boyd, S, Groombridge, S.D, Kemmitt, P.D, Sjogren, T, Morentin Gutierrez, P, de Schoolmeester, J, Swales, J.G, Turnbull, A.V, Wild, M.J. Deposit date: 2013-09-23 Release date: 2014-09-03 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Optimization of Brain Penetrant 11Beta-Hydroxysteroid Dehydrogenase Type I Inhibitors and in Vivo Testing in Diet- Induced Obese Mice. J.Med.Chem., 57, 2014
创建时间：
2013-09-23
