Antiplasmodial Sesquiterpene Alkaloids from the Roots of Maytenus mekongensis
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https://figshare.com/articles/dataset/Antiplasmodial_Sesquiterpene_Alkaloids_from_the_Roots_of_i_Maytenus_mekongensis_i_/2638399
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Eight new sesquiterpene alkaloids (1–8) and four known sesquiterpene alkaloids (9–12) have been isolated from the roots of Maytenus mekongensis. Structures were determined using extensive spectroscopic methods. The relative configuration of 7-epi-mekongensine (2) was established by single-crystal X-ray crystallographic analysis. The alkaloids were evaluated for antiplasmodial activity against Plasmodium falciparum, K1 strain, and for cytotoxicity using a panel of cell lines.
创建时间：
2016-02-23
