Human cyclic GMP-AMP synthase (cGAS) in complex with 2',2'-cGAMP
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Human cyclic GMP-AMP synthase (cGAS) in complex with 2',2'-cGAMP Descriptor: 2-amino-9-[(1R,3R,6R,8R,9R,11S,14R,16R,17R,18R)-16-(6-amino-9H-purin-9-yl)-3,11,17,18-tetrahydroxy-3,11-dioxido-2,4,7,10,12,15-hexaoxa-3,11-diphosphatricyclo[12.2.1.1~6,9~]octadec-8-yl]-1,9-dihydro-6H-purin-6-one, Cyclic GMP-AMP synthase, ZINC ION Authors: Byrnes, L.J, Hall, J.D. Deposit date: 2017-04-03 Release date: 2017-09-27 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.218 Å) Cite: The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition. Protein Sci., 26, 2017
创建时间:
2017-04-03



