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Identification of Ligand-Receptor Pairs that Drive Human Astrocyte Development

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NIAID Data Ecosystem2026-05-02 收录
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We tested a group of five neuronally-secreted ligands and validated their synergistic contributions to astrocyte development within both human cortical organoids and primary fetal tissue. We performed differential gene expression and fold change analysis using data obtained from targeted and bulk RNA-seq of purified fetal astrocyte cell cultures and 3 different organoid lines at three time points.

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2024-05-17
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