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Crystal Structure of EGFR-T790M/C797S in Complex with Reversible Aminopyrimidine 9

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Protein Data Bank Japan2024-02-07 更新2026-04-19 收录
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Crystal Structure of EGFR-T790M/C797S in Complex with Reversible Aminopyrimidine 9 Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor, propan-2-yl 2-[[4-(4-azanylpiperidin-1-yl)-2-methoxy-phenyl]amino]-4-(1-methylindol-3-yl)pyrimidine-5-carboxylate Authors: Niggenaber, J, Kleinboelting, S, Mueller, M.P, Rauh, D. Deposit date: 2022-05-25 Release date: 2023-05-03 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Addressing the Osimertinib Resistance Mutation EGFR-L858R/C797S with Reversible Aminopyrimidines. Acs Med.Chem.Lett., 14, 2023
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2022-05-25
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