Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease
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Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease
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2016-06-16
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Motor neurons derived from human induced Pluripotent Stem Cells.
Time-course transcriptomic analysis of hiPSC-derived Motor Neurons maintained in culture during 1 day, 14 and 28 weeks. RNA from human Spinal Cord tissue is included in the analysis as a control.
NIAID Data Ecosystem50
Recapitulating the Human Segmentation Clock with Pluripotent Stem Cells - RNAseq-based comparison of patient and isogenic rescue/healthy control iPSC lines during in vitro differentiation of human presomitic mesoderm and its derivatives
Pluripotent stem cells (PSCs) have increasingly been used to model different aspects of embryogenesis and organ formation. Despite recent advances in the in vitro induction of major mesodermal lineage
NIAID Data Ecosystem30
The acute myeloid leukemia associated AML1-ETO fusion protein alters the transcriptome and cellular progression in a single-oncogene expressing in vitro induced pluripotent stem cell based granulocyte differentiation model. The acute myeloid leukemia associated AML1-ETO fusion protein alters the transcriptome and cellular progression in a single-oncogene expressing in vitro induced pluripotent stem cell based granulocyte differentiation model
Here we describe the development and characterization of an induced pluripotent stem cell (iPSC) system that allows in vitro differentiation towards different mature myeloid cell types such as monocyt
NIAID Data Ecosystem30
Leucine-Rich Repeat Kinase 2 Influences Fate Decision of Human Monocytes Differentiated from Induced Pluripotent Stem Cells
Mutations in Leucine-rich repeat kinase 2 (LRRK2) are strongly associated with familial Parkinson’s disease (PD). High expression levels in immune cells suggest a role of LRRK2 in regulating the immun
Figshare2016-11-04 更新40
Transcriptome and epigenome dynamic of the clonal heterogeneity of human induced pluripotent stem cells for cardiac differentiation [ATAC-Seq]
Human induced pluripotent stem cells (hiPSCs) generate multiple clones with inherent heterogeneity, leading to variations in their differentiation capacity. Previous studies have primarily addressed l
NIAID Data Ecosystem30
