The intracellular position of genes may impact their expression, but it has not been possible to accurately measure the 3D position of chromosomal loci. In 2D, loci can be tracked using arrays of DNA-
The spatiotemporal chromatin reorganization during hematopoietic differentiation has not been well characterized, which partly limited by the large amounts of starting cells for the current high-throu
The 4D Nucleome Data Portal hosts data generated by the 4DN Network and other reference nucleomics data sets, and an expanding tool set for open data processing and visualization.
This file contains the source data for Extended Data Figure 1c. c, Hi-C matrix (at 5 kb resolution) and loops at the MRR1 region showing two looping silencers (S1 and S2) that exhibit chromatin intera