Incidence and prevalence of generalized pustular psoriasis in multi-ethnic Johor Bahru, Malaysia: a population-based cohort study using routinely captured electronic health records from 2010 to 2020. Supplementary materials

Supplemental Tables and figures of manuscript entitled "Incidence and prevalence of generalized pustular psoriasis in multi-ethnic Johor Bahru, Malaysia: a population-based cohort study using routinely captured electronic health records from 2010 to 2020"
We used data drawn from our local clinical information system, which links primary and secondary care facilities and has captured over 98% of the population in Johor Bahru, to estimate the incidence and prevalence of dermatologist diagnosed GPP over 11 years and examine the frequency of GPP flares and trigger factors. We show that:
1. the incidence and prevalence of GPP in Johor Bahru was 27.2 per million person years (95% CI 22.8-31.6) and 198 per million, respectively;
2. incidence and prevalence of GPP varied by age, sex, ethnicity and presence of associated psoriasis vulgaris;
3. common trigger factors of GPP included withdrawal of systemic corticosteroids, infections, and use of traditional medicines;
4. flare frequency and trigger factors varied between GPP patients with and without associated psoriasis vulgaris.

补充了题为《多民族柔佛巴鲁地区泛发性脓疱性银屑病的发病率与患病率：一项基于人群的队列研究，利用2010年至2020年间常规捕获的电子健康记录》的表格和图表。本研究采用源自本地临床信息系统中的数据，该系统连接了初级和二级保健设施，并覆盖了柔佛巴鲁市98%以上的人口，以估算11年间皮肤科医生诊断的泛发性脓疱性银屑病（GPP）的发病率和患病率，并考察GPP的发作频率及触发因素。研究结果表明：1. 柔佛巴鲁地区GPP的发病率和患病率分别为每百万人口27.2例（95% CI 22.8-31.6）和198例；2. GPP的发病率和患病率随年龄、性别、种族以及是否存在寻常型银屑病的相关症状而变化；3. GPP的常见触发因素包括系统性皮质类固醇的撤药、感染以及传统药物的使用；4. 具有和不存在寻常型银屑病相关症状的GPP患者之间，其发作频率及触发因素存在差异。