UK ME/CFS Biobank

Participants: Over 650 participants are included in the study, including ME/CFS participants diagnosed by a physician and compliant with CDC '94 (Fukuda) and Canadian Consensus Criteria (CCC), with case definition compliance available for four other commonly-used criteria. Healthy and MS matched controls are also available. - Mild and Moderate ME/CFS - Severe (Home-Bound) ME/CFS - Multiple Sclerosis - Healthy Controls Samples Available: Over 32,000 aliquots available. - Whole Blood - Serum - Plasma - RBCs - PBMCs (Sodium Heparin and K2 EDTA) - Blood for RNA Extraction (PaxGENE) Associated Data Available: - Baseline Standard Laboratory Tests to exclude comorbidity causes of fatigue - In-person clinical assessment data - Detailed Symptoms Assessments - Demographic information - Standardised instruments of Fatigue Severity and Functional Impairment