Gene Expression Data from Influenza A Virus-Infected and Mock-infected Mouse Eosinophils

Eosinophils are terminally differentiated granulocytes that recently have been shown to become infected with Influenza A Virus (IAV). Here, we investigate transcriptional changes that occur to bone marrow-derived eosinophils following exposure to IAV. Global changes in the transcriptome of bone marrow derived mouse eosiniphils were assessed following mock- and Influenza A virus-infection using Affymetrix mouse gene 2.0 ST microarrays. Bone marrow-derived eosinophils were infected with MOI 0.1 Influenza A Virus strain PR8 for 1h and incubated at 37°C/5% CO2 for a further 23h at a density of 1 million cells/mL.