Comparison of experimentally observed and theoretically predicted loop motions.

a, b, cOverlap between loop reconfiguration observed in experimental structures and the structural change predicted for the loop by the ANM.aHighest overlap achieved by a single mode and corresponding mode number in parentheses.bSlowest ANM mode (in parentheses) that shows an overlap greater than 0.5, and the corresponding overlap.cSlow modes that show overlap greater or equal to 0.5.dThe ratio loop>pANM/loop>prandom (see Eq. 1 and main text).