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Small molecule inhibitor of the KEAP1-NRF2 protein-protein interaction

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Protein Data Bank Japan2024-05-15 更新2026-03-21 收录
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Small molecule inhibitor of the KEAP1-NRF2 protein-protein interaction Descriptor: (3~{S})-3-(4-chlorophenyl)-3-(2-oxidanylidene-1~{H}-pyridin-4-yl)propanoic acid, Kelch-like ECH-associated protein 1 Authors: Davies, T.G. Deposit date: 2019-02-07 Release date: 2019-04-24 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Structure-Activity and Structure-Conformation Relationships of Aryl Propionic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1/Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1/NRF2) Protein-Protein Interaction. J.Med.Chem., 62, 2019
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2019-02-07
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