Derivation of hypoblast stem cells from rat embryonic stem cells.[RNA-seq]

We report the mRNA profiles of single cells with high-throughput sequencing (RNA-seq) of hypoblast stem cells derived from rat embryonic stem cells. The single-cell data was combined with the previously published dataset: transcriptomes of mouse embryo cells (inner cell mass or trophectoderm). The clustering revealed that rat embryonic stem cell-derived hypoblast stem cells were similar to the mouse inner cell mass cells. Overall design: mRNA profiles of 34 single cells and one population control (bulk population) of hypoblast stem cells with RNA-seq.