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Mapping of TDP-43 ubiquitination and acetylation sites

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https://www.omicsdi.org/dataset/pride/PXD030170
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TAR DNA binding protein of 43 kDa (TDP-43) forms aggregates in neurodegenerative diseases, particularly certain forms of frontotemporal dementia and amyotrophic lateral sclerosis. Pathological modifications of TDP-43 include proteolytic fragmentation, phosphorylation, and ubiquitinylation. In this study, we systematically mapped TDP-42 ubiquitination as well as acetylation sites.
创建时间:
2022-04-01
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