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The effect on p53-induced gene transactivation by NEAT1 knockdown.. Homo sapiens

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA339519
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To explore the effect of NEAT1 on gene transactivation induced by p53, we evaluated the changes in gene expression by RNA-seq in NEAT1 knockdown or control U2OS cells. Overall design: Osteosarcoma U2OS cells were transfected with siRNA targeting NEAT1 or negative control siRNA and then treated with nutlin-3a which activates endogenous p53. The change of p53-induced gene transactivation was analyzed.
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2016-08-19
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