Transcriptional pathway signatures for the Aurora inhibitor Danusertib

ChEBI2011-09-19 更新2026-07-21 收录

Aurora激酶抑制剂

药物转录组学特征

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-24547 数据链接链接失效反馈

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Transcriptional pathway signatures for the Aurora inhibitor Danusertib

创建时间：

2011-09-19

Transcriptional pathway signatures for the Aurora inhibitor Danusertib. Homo sapiens

癌症药物转录组学

Aurora激酶抑制剂

Treatment with Aurora inhibitors has been shown to induce diverse biological responses in different tumor cell lines, in part depending on their p53 status. To characterize at the transcriptional leve

NIAID Data Ecosystem80

Binding Selectivity Analysis of AURKs Inhibitors through Molecular Dynamics Simulation Studies - Raw Data

Aurora激酶抑制剂

分子动力学模拟

Aurora kinases (AURKs) have been identified as promising biological targets for the treatment of cancer. In this study, molecular dynamics simulations were employed to investigate the binding selectiv

Figshare2023-11-22 更新40

Discovery and Synthesis of a Pyrimidine-Based Aurora Kinase Inhibitor to Reduce Levels of MYC Oncoproteins

Aurora激酶抑制剂

MYC靶向治疗

The A-type Aurora kinase is upregulated in many human cancers, and it stabilizes MYC-family oncoproteins, which have long been considered an undruggable target. Here, we describe the design and synthe

NIAID Data Ecosystem40

Supplementary Table 5 from An Integrated Chemical Biology Approach Identifies Specific Vulnerability of Ewing's Sarcoma to Combined Inhibition of Aurora Kinases A and B

肉瘤靶向治疗

Aurora激酶抑制剂

XLS file - 11K

NIAID Data Ecosystem50

Supplementary Material for: The Aurora Kinases Inhibitor VE-465 is a Novel Treatment for Glioblastoma Multiforme

胶质母细胞瘤

Aurora激酶抑制剂

Glioblastoma multiforme (GBM) is one of the most common and aggressive types of primary brain tumor. After complete surgical resection combined with radiation and chemotherapy, approximately 10% of pa

DataCite Commons2020-09-02 更新40

Transcriptional pathway signatures for the Aurora inhibitor Danusertib

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