five

Partially replacing cyclophosphamide with bendamustine in a xenogeneic GvHD transplant model

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https://www.ncbi.nlm.nih.gov/sra/SRP395431
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The data uploaded here are raw bulk RNA sequencing data of splenic transcriptomes from immunocompromised (NSG) mice that were used for xenogeneic graft-versus-host disease (GvHD) studies. Mice received 150 cGy of X-ray irradiation on day -1, 5 million human peripheral blood mononuclear cells on day 0 and post-transplant administration of cyclophosphamide (CY 75mg/kg) on day +3 and CY or bendamustine (BEN 15mg/kg) on day +4. Whole spleens were collected at day 31, snap frozen in liquid nitrogen and RNA was extracted with Qiagen RNeasy mini kit. Samples were sent to Novogene for library preparation and sequencing.
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2023-01-19
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