five

The effect of aneuploidy on gene expression

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE23729
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Analysis of the gene expression changes observed in aneuploid b1 integrin YYFF MEFs generated as a result of repeated cytokinesis failure compared to tetraploid wild-type MEFs or tetraploid b1YYFF integrin MEFs. The results reveal aneuploidy-specific gene expression changes, both up-and downregulated genes uniquely detected in the aneuploid MEFs. Total RNA isolated from b1 integrin YYFF and B1 wildtype mouse embryonic fibroblasts that had been passaged on laminin 0, 4 or 8 times (L0, L4 or L8)
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2018-06-14
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