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Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins

ChEBI2014-07-16 更新2026-07-21 收录

肿瘤转移抑制机制

RNA转录后调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-49649 数据链接链接失效反馈

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Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins

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创建时间：

2014-07-16

性腺发育调控

RNA转录后调控

BackgroundDuring zebrafish embryogenesis, microRNA (miRNA) miR-430 contributes to restrict Nanos1 and TDRD7 to primordial germ cells (PGCs) by inducing mRNA deadenylation, mRNA degradation, and transl

NIAID Data Ecosystem90

Additional file 2 of SRSF3 and SRSF7 modulate 3′UTR length through suppression or activation of proximal polyadenylation sites and regulation of CFIm levels

选择性多聚腺苷酸化

RNA转录后调控

Additional file 2.

NIAID Data Ecosystem40

Systematic Mapping of ADAR1 Binding Reveals its Regulatory Roles in Multiple RNA Processing Pathways [CLIP-seq]

RNA转录后调控

RNA-蛋白质相互作用

ADARs are the primary factors underlying A-to-I editing in metazoans. We conducted the first global study of ADAR1-RNA interaction in human cells using CLIP-Seq. In contrast to the expected predominan

NIAID Data Ecosystem30

RNAseq of Zcchc8 mutant mouse embryonic heads

发育分子机制

RNA转录后调控

We identified a germline heterozygous loss-of-function mutation in ZCCHC8, an RNA exosome targeting component, in a family with autosomal dominant pulmonary fibrosis and telomerase RNA insufficiency.

NIAID Data Ecosystem80

NR4A1 and NR4A3 Restrict HSC Proliferation via Reciprocal Regulation of C/EBPa and Inflammatory Signaling

干细胞转录组学

肿瘤转移抑制机制

NR4A nuclear receptors are known tumor suppressors of acute myeloid leukemia and are essential regulators of hematopoietic stem cell (HSC) quiescence. To study the transcriptional consequences of acut

NIAID Data Ecosystem30

Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins

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