DNA polymerase beta substrate complex with templating adenine and incoming Fapy-dGTP analog
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DNA polymerase beta substrate complex with templating adenine and incoming Fapy-dGTP analog Descriptor: 1,2-ETHANEDIOL, 1-[2-amino-5-(formylamino)-6-oxo-1,6-dihydropyrimidin-4-yl]-2,5-anhydro-1,3-dideoxy-6-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-ribo-hexitol, CALCIUM ION, ... Authors: Freudenthal, B.D, Smith, M.R, Wilson, S.H, Beard, W.A. Deposit date: 2018-10-11 Release date: 2019-01-30 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.144 Å) Cite: A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition. Nucleic Acids Res., 47, 2019
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2018-10-11
