m6A mRNA modification is a rheostat to maintain colonic epithelial cell homeostasis [scRNA-seq]
收藏Alliance of Genome Resources2026-08-01 收录
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The function of m6A modification in colonic epithelial cells has been validated in our study that depletion of METTL14 in colonic epithelial cells triggers cell death. To further explore the biological effects of m6A deficiency in colonic epithelial cell heterogeneity, we performed single cell RNA-seq of colonic epithelial cells form 2-week-old Mettl14-KO and WT control mice Single Cell Profiles of Mettl14 WT and Mettl14 KO colonic epithelial cells of two weeks
