Structure of AMPK bound to activator
收藏Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Structure of AMPK bound to activator Descriptor: 1-O-(4,6-difluoro-5-{4-[(2S)-oxan-2-yl]phenyl}-1H-indole-3-carbonyl)-beta-D-glucopyranuronic acid, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, ... Authors: Calabrese, M.F, Kurumbail, R.G. Deposit date: 2018-07-18 Release date: 2018-08-08 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.35 Å) Cite: Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK). J. Med. Chem., 61, 2018
创建时间：
2018-07-18
