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Glycoform analysis of Tg27-passaged classical CJD (CJD-102L) and IPD P102L (GSS-102L) prions transmitted to transgenic 102LL Tg27 and 129MM Tg35c mice.

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https://figshare.com/articles/dataset/_Glycoform_analysis_of_Tg27_passaged_classical_CJD_CJD_102L_and_IPD_P102L_GSS_102L_prions_transmitted_to_transgenic_102LL_Tg27_and_129MM_Tg35c_mice_/1472565
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* Tg27 = 102LL Tg27 † Tg35c = 129MM Tg35 mice congenic on FVB/N genetic background. ‡ Glycoform ratios of PrPSc propagated in transgenic mice (n = 4 per line) inoculated with Tg27-passaged classical CJD and IPD P102L prions has been compared with the human T2 MM glycoform ratio (n = 11) [31]. Data show mean ± sem. P values relate to comparison with classical CJD T2 MM (unpaired two-tailed t-test). Glycoform analysis of Tg27-passaged classical CJD (CJD-102L) and IPD P102L (GSS-102L) prions transmitted to transgenic 102LL Tg27 and 129MM Tg35c mice.
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2015-07-02
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