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Crystal structure of EGFR 696-1022 WT in complex with AZD9291 prepared by cocrystallization

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Protein Data Bank Japan2024-10-09 更新2026-03-21 收录
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Crystal structure of EGFR 696-1022 WT in complex with AZD9291 prepared by cocrystallization Descriptor: CHLORIDE ION, Epidermal growth factor receptor, N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide Authors: Yun, C.H, Zhu, S.J, Yan, X.E. Deposit date: 2019-04-25 Release date: 2020-04-29 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.307 Å) Cite: Structural Basis of AZD9291 Selectivity for EGFR T790M. J.Med.Chem., 63, 2020
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2019-04-25
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