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A dataset exploring the correlation between LPCAT3 and both glycolipid metabolism and type 2 diabetes mellitus
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相关数据集
Gene expression signatures for human non-diabetic (hND) islets and human type 2 diabetes mellitus (hT2DM) islets
We employed a microarray as a discovery platform to identify the differential gene expressions between hND islets and hT2DM islets. 4805 genes with differential expression (fold change >2) were manife
NIAID Data Ecosystem50
RNA-seq of isolated pancreatic islets from beta-cell-specific Jazf1 knock-out mice
Genome-wide association studies (GWAS) have identified several susceptibility loci for T2D. Among these loci, juxtaposed with another zinc finger protein 1 gene (JAZF1) has been shown as one of the to
NIAID Data Ecosystem30
Underlying data for figures – Part 1: standard diet.
Data supporting “The KCNJ11-E23K gene variant reduces glucose tolerance and accelerates diet-induced diabetes progression in mice by impairing glucose-induced insulin secretion”. Underlying data for
NIAID Data Ecosystem20
Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories toward type 2 diabetes. Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories toward type 2 diabetes
To gain insight into the history of islet cell deterioration along the progression from normal glycemic regulation to T2D, we collected surgical pancreatic tissue samples from 133 metabolically phenot
NIAID Data Ecosystem40
Disturbance of lipid and glucose metabolism induce beta cell dedifferentiation in Ins-1 cell line
In this study, we tried to clarify whether abnormal glucose and lipid metabolism can lead to beta cell dedifferentiation in vitro , and whether there is the role of transcription factor Foxo1 in this
NIAID Data Ecosystem30
